With the frequent occurrence of natural disasters and the acceleration of urbanization, it is necessary to carry out efficient evacuation, especially when earthquakes, fires, terrorist attacks, and other serious threats occur.However, due to factors such as small targets, complex posture, occlusion, and dense distribution, the current mainstream al
Cytokinesis in vertebrate cells initiates by contraction of an equatorial actomyosin network composed of randomly oriented filaments
The actomyosin ring generates force to ingress the cytokinetic cleavage furrow in animal cells, yet its filament organization and the mechanism of contractility is not well understood.We quantified actin filament order in human cells using fluorescence polarization microscopy and found that cleavage furrow ingression initiates by contraction of an
Determinants of Human African Trypanosomiasis Elimination via Paratransgenesis.
Human African trypanosomiasis (HAT), transmitted by tsetse flies, has historically infected hundreds of thousands of individuals annually in sub-Saharan Africa.Over the last decade, concerted control efforts have reduced reported cases to below 10,000 annually, bringing complete elimination within reach.A potential technology to eliminate HAT invol